Danon-Hersch, Nadia

Rodondi, Nicolas

Santos-Eggimann, Brigitte

Spagnoli, Jacques

Serveur académique lausannois

 Visualisation detaillée de la communication  Titre: Frailty, chronic diseases and disability in the youngest old: Aninsight from the Lausanne cohort Lc65+Session: B2: Grands défis, grandes étudesJour et horaires dessessions:25/08/2011   16:00-17:30Heure de la présentation: 16:20 - 16:35Session (salle): B2Auteur/Intervenant: Danon-Hersch, NadiaOrganisation/institution: IUMSP LausanneCo-auteur 1: Nicolas Rodondi, Department of Ambulatory Care and CommunityMedicine, University of Lausanne, SwitzerlandCo-auteur 2: Jacques Spagnoli, Institut universitaire de médecine sociale etpréventive, CHUVCo-auteur 3: Brigitte Santos-Eggimann, Institut universitaire de médecine socialeet préventive, CHUVFRAILTY, CHRONIC DISEASES AND DISABILITY IN THE YOUNGEST OLD: AN INSIGHT FROMTHE LAUSANNE COHORT LC65+Background:While chronic diseases and disability are often measured for the surveillance of the health state of theyoungest old, frailty has become a recognized dimension that independently predicts adverse healthoutcomes. Our aim was to estimate the prevalence of frailty, disability and chronic diseases in theLausanne cohort Lc65+ at baseline and to identify the chronic diseases most frequently associated withpre-frailty.Design: Cross-sectional analysis of a cohort study at baseline, non-institutionalized general population ofLausanneParticipants: 1422 individuals (59 % women) aged 65 to 70.Measurements: Frailty was assessed according to the five criteria described by Fried et al.: shrinking,weakness, exhaustion, slowness and low activity (frailty: ≥3 criteria fulfilled, pre-frailty: 1-2). Medicaldiagnoses of chronic diseases and limitations in activities of daily living (ADL) were self-reported inquestionnaires.Results: At baseline, 35% of Lc65+ participants reported at least 2 chronic diseases (co-morbidity) and6% reported ADL disability. The most frequent chronic diseases were hypertension (40%) and arthritis(35%). 1416 participants were classified as non-frail (72%), pre-frail (26%) or frail (2%). Across these 3groups, there was a progressive increase in the proportion of women (respectively 57%, 64% and 72%,P=0.006), in the prevalence of co-morbidity (28%, 49% and 78%, P<0.001) and in the prevalence of ADLdisability (2%, 13% and 59%, P<0.001). Weakness was the most frequent frailty criterion (15%). When itwas the only frailty criterion fulfilled, it was significantly associated with coronary heart disease, otherheart diseases, diabetes and arthritis. Similarly, significant associations were identified betweenexhaustion and depression; slowness and osteoporosis.Conclusion: While frailty and disability were rare, co-morbidity and pre-frailty were highly prevalent in theyoungest old. The most prevalent frailty criterion was weakness and it was associated with the presenceof cardio-vascular diseases. Longitudinal studies on the evolution of the pre-frail should explore the roleof potential interactions between individual frailty criteria and specific chronic diseases.  

Frailty, chronic diseases and disability in the youngest old: an insight from the Lausanne cohort LC65+

https://serval.unil.ch/resource/serval:BIB_C7C85599258D.P001/REF.pdf

Frailty, chronic diseases and disability in the youngest old: an insight from the Lausanne cohort LC65+

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Serveur académique lausannois