In our country, the management of lifestyle-related diseases and muscloskeletal disorders in becoming more important with the rapidly advancing aging society. I have conducted both basic and clinical research that could contribute to the amelioration of these diseases from the point of view of a clinician. Specifically, I have identified that skeletal muscle differentiation and developmental abnormalities in vitamin D receptor knockout mice, activated calcium-sensing receptor knock-in mice showed various metabolic abnormalities, regulation of stem cell differentiation by IL-11 and so on. We also conducted nationwide survey of fibroblast growth factor 23-related hypophosphatemic diseases to clarify the prevalence and the clinical presentations of the disorders. In this review, I show an overview of my research works, also including the relation to the latest findings
