Using e+e- annihilation data collected by the CLEO II detector at CESR, we have observed the decay Ds+ → ωπ+. This final state may be produced through the annihilation decay of the i\u3eDs+, or through final state interactions. We find a branching ratio of γ(Ds+ → ωπ+)/γ(Ds+ →ηπ+) = 0.16±0.04±0.03, where the first error is statistical and the second is systematic