We have examined the effect of extracts of the calcium phosphate/poly(DL-lactide-co-glycolide) (CP/PLGA) and cobalt-exchanged hydroxyapatite (CoHAp), on the viability of Saos2 osteoblastlike cells. Extracts were prepared by incubation for 3 days at 37°C in the cultivation medium. Conductivity and pH value of extracts were measured before viability assay. Cell viability was estimated by MTT test performed after 24 h incubation of cells with various concentrations of extracts. Extract of CP/PLGA acted more cytotoxic on osteoblasts than the extract of CoHAp. This difference in the effect of examined extracts can be explained by their different pH value and conductivity

Najman, Stevo

Stojanović, Sanja

Mitrić, Žarko

Ajduković, Zorica

Ignjatović, Nenad

Uskoković, Dragan

English

Serbian Academy of Science and Arts Digital Archive (DAIS)

MATERIALS RESEARCH SOCIETY of SERBIA INSTITUTE of TECHNICAL SCIENCES of SASA VINČA INSTITUTE of NUCLEAR SCIENCES, UNIVERSITY of BELGRADE HYDROGEN STORAGE INITIATIVE SERBIA PROGRAM AND THE BOOK OF ABSTRACTS JOINT EVENT OF THE 11TH YOUNG RESEARCHERS’ CONFERENCE: MATERIALS SCIENCE AND ENGINEERING  AND  THE 1ST EUROPEAN EARLY STAGE RESEARCHERS’ CONFERENCE ON HYDROGEN STORAGE  Edited by:  Jasmina Grbović Novaković Nenad Ignjatović Joint event of the 11th Young Researchers’ Conference: Materials Science and Engineering and   the 1st European Early Stage Researchers’ Conference on Hydrogen Storage  3 Book Title: Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage Program and the Book of Abstracts Publisher:  Materials Research Society of Serbia Institute of Technical Sciences of SASA Vinča Institute of Nuclear Sciences, University of Belgrade For Publisher:  Prof. Dr. Dragan Uskoković Dr. Jovan Nedeljković Academician Zoran Đurić Editors:  Dr. Jasmina Grbović Novaković Prof. Dr. Nenad Ignjatović Design: Dr. Nikola Novaković Technical editor: Aleksandra Stojičić Print: Materials Research Society of Serbia : 170 e­copies  Copyright © 2012 by Materials Research Society of Serbia and others contributors.  All rights reserved. No part of this publication may be reproduced, in any form or by any means, without permission in writing from the publisher Joint event of the 11th Young Researchers’ Conference: Materials Science and Engineering and   the 1st European Early Stage Researchers’ Conference on Hydrogen Storage  110 Y 22 EXAMINATION OF THE INFLUENCE OF NANOMATERIALS CALCIUM PHOSPHATE/POLY­(DL­LACTIDE­CO­GLYCOLIDE) AND COBALT­EXCHANGED HYDROXYAPATITE ON THE VIABILITY OF SAOS­2 CELLS Stevo Najman1, Sanja Stojanović1, Žarko Mitić2, Zorica Ajduković3, Nenad Ignjatović4, Dragan Uskoković4 1University of Niš, Faculty of Medicine, Institute of Biology and Human Genetics, Serbia 2University of Niš, Faculty of Medicine, Department of Pharmacy, Serbia 3University of Niš, Faculty of Medicine, Clinic of Stomatology, Department of Prosthodontics, Niš, Serbia 4Institute of Technical Sciences of SASA, Belgrade, Serbia We  have  examined  the  effect  of  extracts  of  the  calcium  phosphate/poly­(DL­lactide­co­glycolide) (CP/PLGA) and cobalt­exchanged hydroxyapatite (CoHAp), on the viability of Saos­2 osteoblast­like cells. Extracts were prepared by incubation for 3 days at 370C in the cultivation medium. Conductivity and pH value of extracts were  measured  before  viability  assay.  Cell  viability  was  estimated  by MTT  test performed after 24 h  incubation of cells with various concentrations of extracts. Extract  of  CP/PLGA  acted  more  cytotoxic  on  osteoblasts  than  the  extract  of CoHAp.  This  difference  in  the  effect  of  examined  extracts  can  be  explained  by their different pH value and conductivity. E­mail of corresponding author: s.sanja88@gmail.com Phone +381 62 1348516 CIP - Каталогизација у публикацији Народна библиотека Србије, Београд 66.017/.018(048)(0.034.2) 662.769.2.032:546.112(048)(0.034.2) 661.96.076(048)(0.034.2) YOUNG Researchers Conference Materials       Sciences and Engineering (11 ; 2012 ;         Beograd)    Program ; and the Book of Abstracts      [Elektronski izvor] / Eleventh Young          Researchers' Conference Materials Sciences    and Engineering and The First European Early  Stage Researchers' Conference on Hydrogen     Storage, Belgrade, December 3rd-5th, 2012 ;   [organized by] Materials Research Society of  Serbia ... [et al.] ; [edited by Jasmina      Grbović Novaković, Nenad Ignjatović]. -       Belgrade : Materials Research Society of      Serbia : Institute of Technical Sciences of   SASA : Vinča Institute of Nuclear Sciences,   2012 (Belgrade : Materials Research Society   of Serbia). - 1 elektronski optički disk      (CD-ROM) ; 12 cm Sistemski zahtevi: Nisu navedeni. - Nasl. sa  naslovnog ekrana. - Tiraž 170. - Registar. ISBN 978-86-7306-122-1 1. European Early Stage Researchers          Conference on Hydrogen Storage (1 ; 2012 ;    Beograd) 2. Materials Research Society of     Serbia (Beograd) a) Наука о материјалима - Апстракти b)      Техничк и материјали - Апстракти c) Водоник - Коришћење - Апстракти d) Водоник -       Ускладиштење - Апстракти COBISS.SR-ID 195039500 

Examination of the influence of nanomaterials calcium phosphate/poly(DL-lactide-co-glycolide) and cobalt-exchanged hydroxyapatite on the viability of Saos-2 cells

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Examination of the influence of nanomaterials calcium phosphate/poly(DL-lactide-co-glycolide) and cobalt-exchanged hydroxyapatite on the viability of Saos-2 cells

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