Cozzoli, Liliana

University of Groningen

   University of GroningenControlling the self-assembly of amphiphiles using DNA G-quadruplexesCozzoli, LilianaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2018Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Cozzoli, L. (2018). Controlling the self-assembly of amphiphiles using DNA G-quadruplexes. [Groningen]:University of Groningen.CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 13-11-2019     Controlling the self-assembly of amphiphiles using DNA  G-quadruplexes              Liliana Cozzoli                                   The work described in this thesis was carried out at the Stratingh Institute for Chemistry, University of Groningen, the Netherlands.  This work was financially supported by the Zernike Institute for Advanced Materials.  Copyright©2018 L.Cozzoli. All rights reseved. No parts of this book may be reproduced or transmitted in any form or by any means without prior written permission of the author.  Cover design: ©evelienjagtman.com  ISBN: 978-94-034-1158-3 (print) ISBN: 978-94-034-1157-6 (digital)  Printed by Ridderprint BV, Ridderkerk, the Netherlands.    Controlling the self-assembly of amphiphiles using DNA  G-quadruplexes   PhD thesis   to obtain the degree of PhD at the University of Groningen on the authority of the Rector Magnificus Prof. E. Sterken and in accordance with the decision by the College of Deans.  This thesis will be defended in public on   Friday 16 November 2018 at 11.00 hours  by   Liliana Cozzoli   born on 23 June 1987 in Trani, Italy   Supervisors Prof. J.G. Roelfes  Prof. B. Poolman    Assessment Committee Prof. A. Herrmann  Prof. M.D. Witte  Prof. E. Stulz            In ricordo di zio Raffaele   “Don’t believe what your eyes are telling you. All they show is limitation. Look with your understanding. Find out what you already know and you will see the way to fly.” (Richard Bach, Jonathan Livingston Seagull)       7 Table of Contents  Chapter 1 DNA G-quadruplexes in nanotechnology and supramolecular chemistry  9 Chapter 2 Responsive DNA G-quadruplex micelles 33 Chapter 3 Design of molecular aptamer beacons for ATP-triggered cargo release  53 Chapter 4 DNA G-quadruplex templated oligomerization of a pore forming peptide  77 Chapter 5 Synthesis of photocleavable amphiphiles: toward light-controlled self-assemblies  107 Chapter 6 Conclusion and perspectives 131 Appendices Samenvatting 145  Acknowledgments 149   

Controlling the self-assembly of amphiphiles using DNA G-quadruplexes

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Controlling the self-assembly of amphiphiles using DNA G-quadruplexes

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