Teaching on topics of race and racism presents unique challenges to leaders in the university classroom setting. Despite an increasing number of instructors bringing a critical analysis of racial in/justice to their curriculum, many report challenges in teaching this content effectively. In this article, we address these challenges. We define common challenges in teaching racial content and articulate four principles for course planning around topics of race, racism, and racial justice. Then, drawing on a systematic review of scholarship examining issues of difference within a diverse range of disciplinary settings, we introduce a set of five pedagogical strategies, and supporting classroom practices, that will help instructors effectively manage everyday classroom interactions. This article contributes to the vast literature on teaching race and anti-racist education by synthesizing guiding pedagogical principles for course planning and classroom management that are applicable in a wide array of disciplinary contexts and providing concrete strategies that committed instructors, at varying levels of experience, can implement in their courses