Muzyka, N.Y.

Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету

388Muzyka N.Y.EXPERIMENTAL STUDY OF PHARMOCOLOGICAL PROPERTIES OF A NEWHERBAL PREPARATION OF ALTABOR SUPPOSITORIESDepartment of PharmacyBukovynian State Medical UniversityNowadays, prostate diseases, in particular, chronic prostatitis is considered to be one ofthe acute medical and social problems. It prevails among urological diseases and causesinfertility, impotence. According to recent studies, approximately 30-45% of men suffer fromchronic prostatitis. In other words, almost every third middle-aged man in Ukraine is diagnosedwith inflammation of the prostate. This problem is extremely serious as there is the tendency ofthe number of patients with chronic prostatitis to increase, which, in turn, takes place due to thedecrease in the immunoresistance of a body and increased exposure to adverse environmentalconditions.Pharmacocorrection is etiopathogenetic in nature and involves the use of drugs ofdifferent pharmacological groups (antibacterial, muscle relaxants, antispasmodics, 5-α-reductaseinhibitors, α-blockers, herbal drugs, etc.) The leading mechanisms of prostate pathology are notprecisely established. That is why the effectiveness of many drugs has not been confirmed interms of evidence-based medicine. Prostate protectors are especially highlighted in the list ofdrugs used to treat prostatopathy. These drugs have a cytoprotective effect, inhibit the process ofexcessive peroxidation, improve microcirculation in prostate tissues, provide high resistance tothe development of inflammatory reactions, hyper- and neoplasia in the prostate etc.The choice of domestic prostate protectors is rather limited in Ukraine. That is whypeople use imported drugs for the treatment of prostatitis. Unfortunately, this type of treatmentremains unaffordable for many people. As a consequence, the development and implementationof effective and safe domestic drugs are absolutely essential for the treatment and prevention ofprostatitis.Novychenko S.D.CHARACTERISTICS OF HYPERTENSION IN PATIENTS WITH DIABETICNEPHROPATHYDepartment of PharmacologyBukovinian State Medical UniversityHemodynamic disturbances, occurring early or late as response to any pathologicalprocesses in the kidneys, are of great significance nowadays in the development of progressivenessof chronic kidneys disease (CKD). Dystrophic and scleral pathological processes that have more orless pronounced diffuse character, considered to acquire steady progression just due to stablehemodynamic changes. Kidney Doppler ultrasonography as relatively new ultrasound method ofinvestigation of the organ bloodcirculation, occupied deserving place in cardiology, obstetrics andgynecology, vascular surgery and transplantology.The aim of this abstract was to make better diagnostics and dynamic control of the quality oftreatment of patients suffering from chronic kidney disease with arterial hypertension presence bymeans of color duplex Doppler ultrasonography investigation of the renal organ blood flow. Thestudy involved 55 men (41.98%) and 76 women (58.02%) aged 29-65 years (mean age 46.50±2.25years) with the 5-10 year history of CKD and hypertension.All patients underwent Dopplerultrasound renal scanning to evaluate morphological changes of kidney structure and patterns of therenal vascularization. Investigation was carried out in the triplex regimen (B-mode ultrasound,colour duplex scanning, mapping, and spectral analysis of Doppler shift frequency) withmeasurement of the peak systolic velocity (Vs), end-diastolic velocity (Vd), time-averagedmaximum blood flow rate (TAMX) in а.interlobaris, and calculation of the volume velocity (Vvol)and renal resistive index (RRI = (Vs–Vd)/Vs). All values were calculated automatically.Some patients (from 69 ) with AH during this period of time received lisinopril at a dose of10 mg and amlodipine at a dose of 5 mg (39 patients) with the object to normalize AP and the

Experimental study of pharmocological properties of a new herbal preparation of altabor suppositories

http://dspace.bsmu.edu.ua:8080/xmlui/bitstream/123456789/20031/1/388_Muzyka.pdf

Experimental study of pharmocological properties of a new herbal preparation of altabor suppositories

Abstract

Similar works

Full text

Available Versions

Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету