Khaschuk, V.S.

Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету

303Considering the fact that a significant number of inflammatory processes occur in thebackground of reduced body resistance and dysbiotic changes of the intestine, all patients withexacerbation of CPMS underwent a microbiological examination of the colon cavity in order todetermine the species composition and population level of autochthonous and allochthonousrepresentatives, and degree of dysbiotic changes.The results of microbiological study show characteristic changes in the species compositionof anaerobic and aerobic autochthonous, facultative and allochthonous microflora of the contents ofthe colon cavity, significantly differing from the species composition of the microflora of the coloncavity within normal limits.In patients with CPMS, the main part of the microflora of the colon is represented bybacteroids, lactobacilli, non-pathogenic Escherichia coli, proteas. Physiologically beneficialbifidobacteria are completely eliminated from the colon in 12.7% of patients with sinusitis. Againstthis background, the percentage of patients with facultative opportunistic anaerobic (peptococcus,clostridia) and aerobic (staphylococci) bacteria is increasing. This fact necessitated thedetermination of the population level of all viable microorganisms isolated from the cavity contentsof the colon of patients with CPMS.Characteristic of microbiocenosis of the colon cavity of patients with CPMS is a pronounceddeficiency of autochthonous obligate physiologically useful bifidobacteria and lactobacilli. Thus,the population level of bifidobacteria decreases by 51.04%, lactobacilli - by 23.46%. At the sametime, the number of anaerobic gram-negative bacteroids and aerobic non-pathogenic Escherichiacoli significantly increases in the content of the colon cavity (by 17.59% and 21.49%, respectively).At the same time, the population level of optional opportunistic anaerobic and aerobicmicroorganisms - clostridia, peptococcus, proteins, staphylococci - increases.The results suggest that in CPMS, all patients develop intestinal dysbacteriosis or dysbiosis,mainly of the second degree due to elimination and severe deficiency of indigenous viable bacteria,which reduces the immune status of patients, affects the severity of clinical manifestations of theunderlying disease, including CPMS course. Probiotic drugs have a therapeutic effect not only dueto the direct effect on the opportunistic microflora, but also due to the stimulation of non-specificresistance factors.Khashchuk V.S.ADHESIVE BOWEL OBSTRUCTION SIMULATION AT DIFFERENT SURGERIES INEXPERIMENTAL TRIALS ON RATSDepartment of Pediatric surgery and OtolaryngologyBucovinian State Medical UniversityAccording to scientific studies surgery performed on adhesive bowel obstruction account for2.4% of the total number of operations on the abdominal cavity organs. There is no need toperitoneal defects, because the mesothelium present in the abdominal cavity located on thesedefects, is implanted and prevents the formation of adhesions. Obstruction that develops later than 3weeks after surgery is associated with the transformation of new connective tissue into fibrous scartissue. Adhesive bowel obstruction can be suspected on the basis of symptoms, physicalexamination and risk factors. Usually to confirm the diagnosis, identify the location of theobstruction and complications such as ischemia, necrosis and perforation modern methods ofexamination are required. Adhesions are not always symptomatic; however, in many patients,adhesions lead to a wide range of complications that occur months or even many years aftersurgery. Adhesion-related complications include small bowel obstruction, infertility in women,chronic abdominal or pelvic pain, and difficulty in relaparotomy.In experimental investigation we assessed intraperitoneal adhesions with different surgicalpathologies, such as anastomosis of the small intestine, anastomosis of the large intestine andintestinal ischemia. The purpose of investigation is to study stages of abdominal adhesions in ratsaccording to Zühlke scale (0-4) at that surgeries.304Distribution of operated rats with surgical pathologies (n=30): first group – 10 rats withanastomosis of the small intestine, second group – 10 rats with anastomosis of the large intestine,third group – 10 rats with intestinal ischemia. First open surgery included simulation of surgerytype, second step – relaparotomy for adhesion development assessment. Terms of relaparotomy,assessment of adhesions and observation of them from 5 to 7 days after second operation withoutdividing them according to the age and gender were carried out.In I group (10 rats) in the first 7 days after surgery with adhesion syndrome had 2-3 markaccording to Zühlke scale. In II group (10 rats) adhesion syndrome over 7 days of postoperativeperiod at rats had 0-1 point of estimating. In III group (10 rats) over 7 days of postoperative periodhad 3-4 point of estimating. Du to statistic data indication the most vulnerable process after surgeryis ischemic bowel injury.According to the research, the most pronounced adhesion process was found in the 3rdexperimental group (intestinal ischemia), which is 3-4 points according to the Zühlke classification.The lowest severity of adhesion process was in group 2 (0-1 points). And 2-3 points in the 1st group- anastomosis of small intestine. This trial indicates a high risk of adhesions development in smallintestine ischemia.Khodzinska Yu.Yu.LIFE QUALITY INDICATORS OF SCHOOLCHILDREN BEFORE AND DURING THEIMPLEMENTATION OF HEALTH PROGRAMS.Department of pediatrics, neonatology and perinatal medicineBukovinian State Medical UniversityQuality of life is a multifartorial and includes physical, mental, emotional, and socialfunctioning.  Its development depends on the socioeconomic factors, moreover educational level isthe most significant one. Education implies learning: knowledge, behaviours, skills and attitudesthat can influence health and wellbeing. The health-promoting program has an aim to providesupport and preventive measures to improve the health of school children , which can be associatedwith  their cognitive development, learning, and academic performance. It is a process that lead toincrease young people’s competencies in understanding and influencing lifestyles as well as livingconditions. Instruments for children must be short, simple, and easy to complete, taking intoaccount cognitive developmental level in reading skills and emotional maturity to match differentdevelopmental stages An affordable and common method of assessment quality of life is usingstandard surveys, but some of them are focused on a specific disease and do not pay enoughattention to healthy children.The goal of the research was to identifiy variation of the health-related life qualityindicators during the health-saving program at school. Such program was implemented in secondaryschool of Chernivtsi region and include the elements of breathing exercises according to theStrelnikova method, jogging , eye gymnastic. In general, 45 children of both sexes in age 10-15years were examined. The general condition, self-assessment of health, physical andpsychoemotional functioning was evaluated. Positive assosiations were found between childrens`weekly total physical activity at school  and total health-related quality of life. The schoolers feltless fatigue in the classroom and have a better night's sleep, better indicators of spirometry "flow-volume".To conclude, the health-promoting program at school is a crucial tool for providing ahealthier environment , using interactive learning methods, building better communication andseeking partners and allies in the community,to promote schoolers` health and well-being.

Adhesive bowel obstruction simulation at different surgeries in experimental trials on rats

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Adhesive bowel obstruction simulation at different surgeries in experimental trials on rats

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Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету