The present invention relates to pharmaceutical combinations of at least one TNF inhibitor and riboflavin to treat patients suffering from inflammatory bowel disease (IBD) or other inflammatory conditions (such as rheumatoid arthritis, ankylosing spondylitis, psoriasis, lupus erythematous and multiple sclerosis). This invention also relates to additive and/or combinations of at least one TNF inhibitor and riboflavin. This invention is also related to a method for the treatment or prophylaxis of IBD, which method comprises administering a therapeutically effective amount of TNF inhibitor and riboflavin

Dijkstra, G.

Faber, Klaas Nico

Harmsen, Hermanus Jozef Martinus

Steinert, Robert

Sybesma, Wilbert

Topchyan, Araksya

English

University of Groningen

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel disease(II)Dijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II). (PatentNo. WO2020161089).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 26-12-2020

Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II)

The present invention relates to pharmaceutical combinations of at least one thiopurine and/or at least a pharmaceutically acceptable salt and/or at least one prodrug thereof and riboflavin to treat patients suffering from inflammatory bowel disease (IBD) or other inflammatory conditions. This invention also relates to additive and/or combinations of at least one thiopurine and riboflavin. This invention is also related to a method for the treatment or prophylaxis of IBD or other inflammatory conditions, which method comprises administering a therapeutically effective amount of thiopurine and riboflavin

Dissertations of the University of Groningen

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel diseaseDijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease. (Patent No.WO2020161088).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 10-03-2023

Therapeutic combinations and compositions for the treatment of inflammatory bowel disease

ARTS repository - University of Groningen

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel diseaseDijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease. (Patent No.WO2020161088).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 05-12-2023

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel disease(II)Dijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II). (PatentNo. WO2020161089).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 10-03-2023

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel disease(II)Dijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II). (PatentNo. WO2020161089).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 11-09-2023

Proceedings - University of Groningen

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel diseaseDijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease. (Patent No.WO2020161088).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 11-09-2023

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel disease(II)Dijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II). (PatentNo. WO2020161089).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 05-12-2023

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel diseaseDijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease. (Patent No.WO2020161088).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 07-06-2022

   University of GroningenTherapeutic combinations and compositions for the treatment of inflammatory bowel diseaseDijkstra, G.; Faber, Klaas Nico; Harmsen, Hermanus Jozef Martinus; Steinert, Robert;Sybesma, Wilbert; Topchyan, AraksyaIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2020Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Dijkstra, G., Faber, K. N., Harmsen, H. J. M., Steinert, R., Sybesma, W., & Topchyan, A. (2020).Therapeutic combinations and compositions for the treatment of inflammatory bowel disease. (Patent No.WO2020161088).CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 26-12-2020

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Therapeutic combinations and compositions for the treatment of inflammatory bowel disease (II)

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Dissertations of the University of Groningen

ARTS repository - University of Groningen

Dissertations of the University of Groningen

Dissertations of the University of Groningen

Proceedings - University of Groningen

Proceedings - University of Groningen

ARTS repository - University of Groningen

ARTS repository - University of Groningen

University of Groningen