Bovine theileriosis is caused by the protozoan parasite Theileria annulata and Theileria parva and is transmitted through tick Hyalomma and Rhipicephalus, respectively leading to economic losses and causes devastating losses to the livestock worldwide. This paper deals with clinical signs, diagnosis and treatment of theileriosis in buffalo having 4years of age and clinical signs observed were; high fever (106.7oF), anorexia, enlarge lymph nodes, dyspnoea and ocular discharge with pale mucous membrane. The peripheral blood smear confirmed the presence of Koch blue bodies. The animal was treated with a single dose of Buparvaquone, 2.5 mg/kg i.m. along with supportive therapy
