The paper reports results of one of the largest empirical studies to-date on the impact of design risk management practices on product design success. Through a survey of 224 practices, 38 (in 7 categories) where found to be statistically significant for at least 3 out of 4 performance metrics. The categories are: 1. Organizational Design Experience; 2. Risk Management Personnel and Resources; 3. Tailoring and Integration of Risk Management Process; 4. Risk-Based Decision Making; 5. Specific Mitigation Actions; 6. Monitoring and Review; and 7. Other ISO Risk Management Principles.King Fahd University of Petroleum and Minerals (Center for Clean Water and Clean Energy at MIT and KFUPM (R11-DMN-09))Massachusetts Institute of Technology. Lean Advancement Initiativ