Objective: To analyze the causes of blood donation reaction of university students, propose appropriate preventive measures to avoid blood waste and ensure the quality of the blood. Methods: The university students in Guiyang city were selected from January to December 2010, The cases of blood donation reaction and the causes are analyzed on 7063 college students. Results: Among the 7063 college students, there are 292 students with blood donation reaction, the main cause is psychological factors, followed by fatigue before blood donation, not-ideal blood donation environment, limosis or starvation, etc. It occurs more in the first time donors. blood donors with different times and posture have different adverse reactions. Conclusion: Constantly summarizing experiences, development and implementation of scientific and causable preventive measures, improving the environment for blood donation, strengthening the sense of responsibility and sense of service of blood collection personnel, strengthening psychological nursing, giving donors a warm caring and confidence as far as possible, making donors relax mind and in the best state can help to reduce and prevent the occurrence of blood donation reaction, organize more donators and college students to actively participate in blood donation, in order to promote vigorous, healthy and sustained development of voluntary blood donation. The blood donation adverse reactions of university students are related to the frequency of blood donation and posture, we have developed a series of preventive measures against the causes of blood donation adverse reactions to reduce the incidence of adverse reactions
