Cerebral venous thrombosis at the Hospital Civil de Guadalajara "Fray Antonio Alcalde" [Trombosis venosa cerebral en el Hospital Civil de Guadalajara "Fray Antonio Alcalde"]

Abstract

Introduction: Cerebral venous thrombosis (CVT) is the least common among all sorts of acute cerebrovascular disease, with a hospital frequency reported of 0.43 to 8% in Mexico. CVT has been studied mainly in concentration hospitals in Mexico City; however, its features in other scenarios of the rest of the country are unknown. Objective: To describe the main clinical, therapeutic and radiological features as well as the prognosis of CVT at the Hospital Civil de Guadalajara "Fray Antonio Alcalde". Material and methods: All consecutive patients with diagnosis of CVT between 1999 and 2008, complete data about clinical and radiological characteristics at hospital admittance, as well as the in-hospital evolution and outcome at discharge and during long-term follow-up were registered. Results: A total of 24 patients with mean age of 30 years were included; 20 of them (83%) were women. The course of the CVT was mainly sub-acute with a delay in diagnosis of eleven days. Headache, motor focal signs and cognitive and behavioral disturbances were the most common manifestations. Longitudinal superior sinus was the most affected. Puerperium was the most frequently associated condition to CVT (46%). Hospital stay was 22 days in average and during this lapse, one fourth of patients received anticoagulation. At discharge, mortality rate was 8% with a bad outcome in 50% of cases; however, during a follow-up (17 months in average), 70% observed a good outcome, without CVT recurrence. Conclusion: CVT in our hospital is not different to what has been previously reported in other hospitals in Mexico. The mortality observed was low and the long term prognosis was good

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