ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF UREA/ THIOUREA DERIVATIVES OF 5-METHYL-3-(UREDIOMETHYL)-HEXANOIC ACID

Abstract

A series of urea/ thiourea derivatives of 5-methyl-3-(urediomethyl)-hexanoic acid has been successfully synthesized from the reaction of 3-aminomethyl-5-methylhexanoic acid and aryl isocyanate/ aryl isothiocyanates in presence of triethylamine base in tetrahydrofuran solvent at rt-40C by stirring the contents for 3h

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