User-centered design not only requires designers to analyse and anticipate how users are likely to use a Web application, but also to validate their assumptions with regard to user behaviour in real environments. Cognitive neuroscience, for its part, addresses the questions of how psychological functions are produced by neural circuitry. The emergence of powerful new measurement techniques
allows neuroscientists and psychologists to address abstract questions such as how human cognition and emotion are mapped to specific neural substrates. This paper focus on the validation of user-centered designs and requirements of Web applications by neuroscience techniques and suggest the use of these
techniques to achieve efficient and effectiveness validated designs by real behavior of potential users.Ministerio de Ciencia e Innovación TIN2013-46928-C3-3-RJunta de Andalucía TIC-578
