Bartels, Anna L.

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Dissertations of the University of Groningen

   University of GroningenPathogenetic mechanisms in Parkinson's diseaseBartels, Anna L.IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2010Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Bartels, A. L. (2010). Pathogenetic mechanisms in Parkinson's disease: studies with positron emissiontomography. [S.n.].CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 04-06-2022Ccntrale Mcdische Bibliothcek Groningcn u M C G Stellingen behorende bij het proefschrift L-----..,r�a�.r�no;;:;.genetic mechanisms in Parkinson's disease: studies with Positron Emission Tomography". Anna L. Bartels 1. Dysfunctional blood-brain barrier P-glycoprotein is not a primary causative factor in the etiology of Parkinson's disease. (Chapter 3) 2. Impaired blood-brain barrier P-glycoprotein function is involved in progressive neurodegeneration. (Chapter 4) 3. Decreased blood-brain barrier P-glycoprotein function with aging is involved in vulnerability of the aging brain for accumulation of toxic substances and drugs. (Chapter 5) 4. The distribution volume of p 1 C]-verapamil provides a measure for assessment of regional blood-brain barrier P-glycoprotein function. (Chapters 3-5) 5. The current analysis methods of p 1C]-PK11195 uptake in brain do not provide solid data to assess changes in specific tracer uptake by anti­inflammatory treatment. (Chapter 7) 6. COX-2 inhibition probably prevents up-regulation of P-glycoprotein­expressing vasculature, without an effect on microglia activation. (Chapter 8) 7. De kennis van een gevolg hangt af van de kennis van de oorzaak en sluit die in. (Spinoza, Ethica) 8. What is past is prologue. (Shakespeare, The tempest) 9. Van een theorie is het waarachtig niet de geringste charme dat zij weerlegbaar is. (Nietzsche) 10. Niets geloven we zo stellig, als wat we het minste weten. (]M. de Montaigne) 11. Life is what happens to you, while you're busy making other plans. Q"ohn Lennon) 

Pathogenetic mechanisms in Parkinson's disease:studies with positron emission tomography

https://pure.rug.nl/ws/files/80403901/A.L.Bartels_stellingen.pdf

Pathogenetic mechanisms in Parkinson's disease:studies with positron emission tomography

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