Rizo, Aleksandra

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Dissertations of the University of Groningen

   University of GroningenThe polycomb gene BMI1 in normal hematopoiesis and leukemiaRizo, AleksandraIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:2011Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Rizo, A. (2011). The polycomb gene BMI1 in normal hematopoiesis and leukemia. [S.n.].CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 04-06-2022Stellingen behorde bij het proefschrift The polycomb gene BMll in normal hematopoiesis and leukemia 1. The polycomb-group protein BMll is a cell intrinsic regulator of human stem/progenitor cell self-renewal. This thesis 2. Enforced expression of BMll is a powerful mediator of maintenance and self-renewal of human hematopoietic stem and progenitor cells. This thesis 3. Elevated levels of BMll act as a collaborating event with BCR-ABL to induce leukemic transformation of human cells. This thesis 4. BMll is an attractive candidate for targeting CML patients in blast crisis. This thesis 5. A stem cell is as good as its microenvironment. 6. What is a stem cell today may not be one tomorrow. 7. To the individual who devotes his/her live to science nothing can give more happiness than when the results find practical application. There are not two sciences. There is science and the application of science, and these two are linked as the fruit is to the tree. Luis Pasteur 8. If I have seen further than others, it is by standing upon the shoulders of giants. Isaac Newton 9. There is no harm in doubt and skepticism, for it is through these that new discoveries are made. Richard Feynman 10. If you want to kiss the sky, better learn how to kneel. Bono Aleksandra Rizo, 24 mei 2011 Ccntr .. i}e U Melli:,..:he M Bihliothcek C Grurungcn G 

The polycomb gene BMI1 in normal hematopoiesis and leukemia

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The polycomb gene BMI1 in normal hematopoiesis and leukemia

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