Percutaneous mitral valve repair was introduced a few years ago for patients with symptomatic severe mitral regurgitation and can use two different approaches. The first approach is the edge-to-edge technique, which creates a double mitral valve orifice. The second approach is mitral annuloplasty, which is achieved by introducing a constraining device in the coronary sinus located in the vicinity of the mitral annulus. Preliminary results of percutaneous mitral valve repair are encouraging and show the feasibility of these techniques, which though should be carefully evaluated in comparison with surgery and standard contemporary medical treatment