Berg, Rolf Henrik

Buchardt, Ole

Engholm, Michael

Nielsen, Peter E.

A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than a corresponding DNA strand, and exhibit increased sequence specificity and binding affinity. The peptide nucleic acids of the invention comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases attached to a polyamide backbone. Some PNAs of the invention also contain C1-C8 alkylamine side chains

Online Research Database In Technology

Peptide Nucleic Acids Having 2,6-Diaminopurine Nucleobases

http://orbit.dtu.dk/ws/files/58067655/US6613873.pdf

Peptide Nucleic Acids Having 2,6-Diaminopurine Nucleobases

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