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Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung adenocarcinoma cells with an epithelial-mesenchymal transition phenotype
Authors
Hasegawa T
Hirai S
+8 more
Kojima T
Niki T
Nishikiori H
Sakuma Y
Takahashi H
Watanabe A
Yamada G
Yamaguchi M
Publication date
1 December 2017
Publisher
札幌医科大学
Abstract
EGFR mutant肺腺癌には逆説的ながらEGFRへの依存性が低い癌細胞が含まれている。本研究では,“EGFR非依存性”EGFR mutant肺腺癌には異性化酵素Pin1に強く依存するものが存在することを示した
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SIKOR - Sapporo Medical University Information and Knowledge Repository / 札幌医科大学学術機関リポジトリ
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Last time updated on 17/10/2019