The sandwich panels, with plain and shallow grain pressed metal plate as the face sheets, and glass wools, rigid polyurethane foam, and rock wools as core materials, have excellent heat insulation and mechanical behavior, and been used as curtain walls for tall buildings in recent years in China. Since wind load and temperature action are the main actions for curtain walls, the sandwich panels are flexural members. In this paper, the design method and design formula of flexural load-carrying capacity and flexural deflection of a kind of sandwich plates with different metal panel on both sides are discussed and proposed. This proposed method considers the different load types, like uniform load, concentrated load, and temperature action, and different core materials. The FE Method can be verified by comparing on shear force distribution coefficients for different sandwich panels with same metal panels on both sides between FE results and calculated results. Then the FE Method can be used to verify the proposed method for shear force distribution coefficients of sandwich plates with different metal panel on both sides. Finally, the proposed method for bending load-carrying capacities for sandwich plates with different metal panel on both sides is verified using FE Method. These verifies show that the proposed method for shear force distribution coefficients and bending load-carrying capacities for sandwich plates with different metal panel on both sides is safe and suitable