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Persistent Edematous-plaque Photosensitivity Observed with Sitagliptin Phosphate (Januvia®)
Authors
Antoinette F. Hood
Jerome Z. Litt
+4 more
Ryan K. Rader
Thomas P. Schuman
William V. Stoecker
Sherea Stricklin
Publication date
1 January 2012
Publisher
Scholars\u27 Mine
Abstract
Photosensitivity to sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is reported. No previous reports of photosensitivity to any DPP-4 inhibitors are known. Physical examination of the patient revealed edematous plaques confined to sun-exposed areas of the skin. An unusual finding in this case was the spongy sensation upon palpation of the plaques. Histopathology revealed parakeratosis and abundant eosinophils, supporting the clinical impression of cutaneous drug sensitivity. The eruption finally cleared, approximately two years after onset. © 2012 Dermatology Online Journal
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Missouri University of Science and Technology (Missouri S&T): Scholars' Mine
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Last time updated on 17/10/2019