The effect of oral administration of an optimum dose of ammonium monovanadate was studied in hosts bearing a transplantable ascitic lymphoma. This was supported by the biochemical indices relating to markers like reduced glutathione (GSH), extent of lipid peroxidation and activities of glutathione per-oxidase (GPx) in hepatic tissues of the experimental animals. These biochemi-cal parameters showed substantial alterations during the period of tumor progres-sion in the experimental group treated with a low dose of vanadium (0.005 ,μ-M) suggesting a possible correlation between the observed variation in these markers and the survival rates in the animals receiving vanadium treatment
