OBJECTIVE: Preparation for the conduct of multi-country research is analogous to securing the aircraft and taxiing down the runway in anticipation of flight. The process of designing and implementing data analysis strategies for a research project entitled “Nursing practice in HIV prevention and care in Sub-Saharan Africa and the Caribbean” is described. Management of qualitative data from two of the project tools will be used to highlight the ethical considerations, electronic and telecommunications challenges, wide range of expertise, and other practical and logistical issues that were encountered. METHODS: Investigators, collaborators, research assistants, and students representing five countries worked together to develop protocols and frameworks for the management and analysis of data. RESULTS: Analysis teams identified barriers and created innovative strategies for learning the necessary skills to manage data efficiently and rigorously. Because the intent of the study is to build leadership capacity for research and policy development among nurses in low and middle income countries, identifying and addressing best practices collaboratively was an important initial part of the process. CONCLUSIONS: A successful journey begins by ensuring all team members are on board. The authors will discuss the communication strategies and resources that were established in order to maximize capacity building and consistent analysis in this multi-country program of research
