How the environment shapes genetically induced seizure activity in rats

Abstract

Item does not contain fulltextUnderling biology that governs the age-dependent seizure susceptibility is a new, exciting research field for every pediatric epileptologists and developmental nouroscientists. From daily practice, clinicians are well aware about a close correlation between the degree of seizure susceptibility and age of the individual. Pathophysiological mechanisms involved are multiplex, including race/gender nutrition, receptors/ion channels, dysgenesis, pharmacokinetics of AEDs, acute illnesses/inflammation and many others. In this book, the top-ranked experts contributed their original papers dealing with the cutting edge of knowledge in various aspects of underlying biology. Each article presents a comprehensive review of the subjects, guiding the readers to better understanding the contemporary status of achievements in this challenging research field