Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject

Hargis, Billy M.

Morgan, Marion

Pumford, Neil R.

Shivaramaiah, Srichaitanya

Tellez, Guillermo L.

Wolfenden, Amanda

English

UARK (University of Arkansas )

University of Arkansas, Fayetteville ScholarWorks@UARK Patents Granted 9-22-2020 Mucosal adjuvants and delivery systems Billy M. Hargis Neil R. Pumford University of Arkansas, Fayetteville Marion Morgan Srichaitanya Shivaramaiah University of Arkansas, Fayetteville Guillermo L. Tellez University of Arkansas, Fayetteville See next page for additional authors Follow this and additional works at: https://scholarworks.uark.edu/pat Citation Hargis, B. M., Pumford, N. R., Morgan, M., Shivaramaiah, S., Tellez, G. L., & Wolfenden, A. (2020). Mucosal adjuvants and delivery systems. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/394 This Patent is brought to you for free and open access by ScholarWorks@UARK. It has been accepted for inclusion in Patents Granted by an authorized administrator of ScholarWorks@UARK. For more information, please contact scholar@uark.edu. Inventors Billy M. Hargis, Neil R. Pumford, Marion Morgan, Srichaitanya Shivaramaiah, Guillermo L. Tellez, and Amanda Wolfenden This patent is available at ScholarWorks@UARK: https://scholarworks.uark.edu/pat/394 

Mucosal adjuvants and delivery systems

ScholarWorks@UARK

University of Arkansas, Fayetteville ScholarWorks@UARK Patents Granted 9-22-2020 Mucosal adjuvants and delivery systems Billy M. Hargis Neil R. Pumford Marion Morgan Srichaitanya Shivaramaiah Guillermo L. Tellez See next page for additional authors Follow this and additional works at: https://scholarworks.uark.edu/pat Inventors Billy M. Hargis, Neil R. Pumford, Marion Morgan, Srichaitanya Shivaramaiah, Guillermo L. Tellez, and Amanda Wolfenden 

University of Arkansas, Fayetteville ScholarWorks@UARK Patents Granted 4-16-2019 Mucosal adjuvants and delivery systems Billy M. Hargis University of Arkansas, Fayetteville Neil R. Pumford University of Arkansas, Fayetteville Marion Morgan Srichaitanya Shivaramaiah University of Arkansas, Fayetteville Guillermo L. Tellez University of Arkansas, Fayetteville See next page for additional authors Follow this and additional works at: https://scholarworks.uark.edu/pat Citation Hargis, B. M., Pumford, N. R., Morgan, M., Shivaramaiah, S., Tellez, G. L., & Wolfenden, A. (2019). Mucosal adjuvants and delivery systems. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/366 This Patent is brought to you for free and open access by ScholarWorks@UARK. It has been accepted for inclusion in Patents Granted by an authorized administrator of ScholarWorks@UARK. For more information, please contact scholar@uark.edu. Inventors Billy M. Hargis, Neil R. Pumford, Marion Morgan, Srichaitanya Shivaramaiah, Guillermo L. Tellez, and Amanda Wolfenden This patent is available at ScholarWorks@UARK: https://scholarworks.uark.edu/pat/366 

https://scholarworks.uark.edu/cgi/viewcontent.cgi?article=1356&context=pat

Mucosal adjuvants and delivery systems

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