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Urine macrophage migration inhibitory factor in pediatric systemic lupus erythematosus
Authors
A. Bedayat
H. Chalian
+7 more
M. Chalian
N. Hooman
R. Hoseini
S. Mahdavi
H. Otukesh
S. Sabaghi
R.S. Yazdi
Publication date
1 January 2007
Publisher
Abstract
We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine samples. MIF/creatinine (Cr) ratio directly correlated with disease activity and it does not have any significant difference between inactive disease and normal ones. We found that the urine MIF/Cr ratio not only differentiates active disease from inactive disease and normal ones but also correlates with the activity indices of renal pathology. © Clinical Rheumatology 2007
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eprints Iran University of Medical Sciences
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oai:eprints.iums.ac.ir:9962
Last time updated on 10/10/2019