Clostridium difficile infection: A review

Abstract

Clostridium difficile, as one of the main bacterial causes of diarrhea, is an important healthcare-associated pathogen. It is also the main causative agent of antibiotic-associated diarrhea and pseudomembranous colitis. The C. difficile infection is a life threatening disease, and there is an urgent need to control its spread in healthcare centers. This review summarizes the most recent work on epidemiology and interactions between host and C. difficile. © 2018 Wolters Kluwer Health, Inc