Babaie, A.

Hosseinzadeh, S.

Kabiri, M.

Nazari, H.

Sadegzadeh, N.

Soleimani, M.

Soufi Zomorrod, M.

Tasharrofi, N.

Among different tissues, endothelial/cardiac types require specific factors to promote myocardial regeneration after occurred injuries. Herein, cardiac stem cells (CSCs) as the major cell population that involved in cardiovascular repair were selected to study the role of polyethyleneimine (PEI) agent on endothelial differentiation. After preparation of electrospun network of PEI with polyacrylonitrile, the related characterizations were carried out including scanning electron microscope (SEM), field-emission SEM, water contact angle, Fourier transform infraredÂ spectroscopy and mechanical properties. Also, the release kinetic of the corresponding agent was studied up to 7 days. The cell differentiation studies were done in the following with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromideÂ assay, Real-time polymerase chain reaction and immunostaining method. The whole obtained results approved the higher differentiation of CSCs into endothelial/cardiac cells. Finally, it is recommended that the PEI delivering increases the healing potency of CSCs and accordingly the regeneration speed of damaged cardiovascular tissue would be improved. Â© 2018 Wiley Periodicals, Inc

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Polyethylenimine: A new differentiation factor to endothelial/cardiac tissue

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Terms and conditions                Privacy policyCopyright © 2018 Elsevier B.V.  All rights reserved. Scopus® is a registered trademark of Elsevier B.V.DocumentsExport Date: 25 Dec 2018Search: AF-ID("Iran University of Medical Sciences" 60024852) OR AF-...1) Hosseinzadeh, S., Nazari, H., Sadegzadeh, N., Babaie, A., Kabiri, M., Tasharrofi, N., Soufi Zomorrod,M., Soleimani, M.Polyethylenimine: A new differentiation factor to endothelial/cardiac tissue(2019) Journal of Cellular Biochemistry, 120 (2), pp. 1511-1521. Cited 1 time.1) https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052834285&doi=10.1002%2fjcb.27287&partnerID=40&md5=427d1b377cd274fb4c6467f4b7dcc504DOI:  10.1002/jcb.27287Document Type:  ArticlePublication Stage:  FinalSource:  ScopusSearch: AF-ID("Iran University of Medical Sciences" 60024852) OR AF-ID("Iran University of MedicalSciences  Faculty of Medicine" 60007790) OR AF-ID("Pars Advanced and Minimally Invasive MedicalManners Research Center" 60109876) OR AF-ID("Iran University of Medical Sciences  Growth andDevelopment Research Center" 60112932) OR AF-ID("Iran University of Medical Sciences  Instituteof Endocrinology and Metabolism Research and Training Center" 60112584) OR AF-ID("IranUniversity of Medical Sciences  Endocrine Research Center" 60112585) OR AF-ID("Iran University ofMedical Sciences  Prevention of Cardiovascular Diseases" 60112933) OR  (...) OR AF-ID("TehranPsychiatric Institute" 60077825) AND ( LIMIT-TO ( PUBYEAR,2019) )

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eprints Iran University of Medical Sciences

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eprints Iran University of Medical Sciences