Studies suggest that family members of patients in the icu and true negative changes in your life as stress, physical, emotional - psychological and social experience Members stress has increased over time, eventually resulting in impaired function and role of the family. This alone can cause severe fouling in distress within the family system. Therefore, this study compared stress, anxiety and depression in family members of patients hospitalized in intensive ccu, icu in Iran. This descriptive - analytical comparison. On 200 first-degree family members of the patients admitted to the ICU ccu, icu hospital Anbiya paced Zahedan in 2014. Stress and depression DASS questionnaire collected data using spss software and parametric t-test and chi-square test was used for statistical analysis. Our findings in the study of stress, anxiety and depression in family members of ICU patients in ICU, CCU showed. ICU hospitalized patients, family stress, anxiety and depression in family members of patients with more than hospitalized in CCU experience. When a patient is admitted in intensive care unit patients and family members should be treated with respect and make a decision that impacts the physiological and psychological symptoms in family members. Members often stress, anxiety and depression so it seems the nurses support patients and families through health communication proper and assist them in the discharge of feelings and emotions, to create hope in families and reduce their stress levels