Trends in ovarian cancer incidence in Iran

Abstract

Background: Cancer is amajorcause of morbidityandmortality,amongwhichovarian cancer has a high incidenceandcase fatality. Gaining insight into the epidemiology and trends of ovarian cancer can be very influential in cancer screening and treatments programming. This study aimed to investigate the trends in the incidence of ovarian cancer in Iran, because this issue has been neglected so far. Methods: This study is a re-analysis of existing data from the cancer data recording system in Iran during the years 2003 to 2009. The incidence rates reported were standardized according to the world health organization (WHO) and the trend in the incidence of this disease was determined by STATA software and the significance of the morbidity trend diagram was also derived via WINPEPI software. Results: The statistics of cancer registry center shows an increasing trend of ovarian cancer from 2003 to 2008, while it decreased from 2008 to 2009. During this period, 6078 cases of ovarian cancer were registered in Iran, increasing from 591 cases in 2003 to 1077 in 2009, which shows an approximately 2-fold increase in the incidence of registered cases. During these seven years, the highest incidence rate was seen in Markazi province with 6.33 per 100,000 persons and the least in Kohkiloye-va-Boyerahmad province with zero incidence. Almost all provinces, except a few, had increasing incidence of ovarian cancer. Conclusions: According to the results of the study, the incidence of ovarian cancer is increasing in Iran, especially in the central and northwestern regions of the country. This increase may be due to changing the patterns of risk factors for this disease, such as changes in lifestyle in the population, which will lead to changes in the incidence of the disease. Hence, due to the increase in incidence of this cancer, it is recommended to implement screening and early detection programs in high risk areas and populations. © 2016, Iranian Journal of Cancer Prevention