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Assessment of optic disc and ganglion cell layer in diabetes mellitus type 2
Authors
G. Deda
H. Kaya
+4 more
A. Kaşikçi
E. Pekel
Gökhan Pekel
G. Tufaner
Publication date
1 January 2017
Publisher
'Ovid Technologies (Wolters Kluwer Health)'
Doi
Cite
Abstract
The purpose of this study was to compare the optic disc parameters, retinal nerve fiber (RNFL), and macular ganglion cell layers between patients with diabetes mellitus (DM) type 2 and healthy controls. In this cross-sectional study, 69 eyes of 69 diabetic patients without diabetic retinopathy and 47 eyes of 47 healthy controls were included. Optic disc parameters (i.e., rim area, disc area, cup to disc ratio, cup volume), RNFL, and macular ganglion cell-inner plexiform layers (GCL+IPL) thickness were measured by means of spectral domain optical coherence tomography. There were not statistically significant differences between the diabetic patients and healthy controls in terms of RNFL thickness (P=.32), rim area (P=.20), disc area (P=.16), cup volume (P=.12), and average macular GCL+IPL thickness (P=.11). Nevertheless, binocular RNFL thickness symmetry percentage (P=.03), average cup to disc ratio (P=.02), and superior-nasal macular GCL+IPL thickness (P=.04) were statistically significantly different in the diabetic and control groups. Diabetic patients without retinopathy have more binocular RNFL thickness asymmetry, higher cup to disc ratio, and thinner sectoral macular GCL+IPL when compared to healthy controls. Our results may support the statement that DM causes inner retinal neurodegenerative changes. © 2017 the Author(s). Published by Wolters Kluwer Health, Inc
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Pamukkale Üniversitesi Açık Erişim Arşivi
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Last time updated on 05/09/2019
Pamukkale Üniversitesi Açık Erişim Arşivi
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:acikerisim.pau.edu.tr:1149...
Last time updated on 05/09/2019
Pamukkale Üniversitesi Açık Erişim Arşivi
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:acikerisim.pau.edu.tr:1149...
Last time updated on 05/09/2019