Phytochemical and biological study of Vernonia tweediana Baker (Asteraceae)

Abstract

A mistura de α-amirina, β-amirina e lupeol e o ácido palmítico puro foram os principais constituintes químicos isolados do extrato clorofórmio da parte aérea de V. tweediana. Lupenil palmitato puro e a mistura de α-amiril palmitato e β-amiril palmitato foram isolados a partir do extrato clorofórmio das raízes. As estruturas foram caracterizadas por métodos químicos e espectroscópicos. Também foram investigadas as atividades biológicas dos extratos hexano, clorofórmio, acetato de etila e metanol das partes aéreas e raízes de V. tweediana. Os extratos mostraram atividades boas a moderadas.The mixture of α-amyrin, β-amyrin and lupeol and pure palmitic acid were the main constituents isolated from chloroform extract of the aerial part of V. tweediana. Pure lupenyl palmitate and a mixture of α-amyril palmitate and β-amyril palmitate were isolated from chloroform extract of the roots. Their structures were established by chemical and spectroscopic methods. The biological activities of the hexane, chloroform, ethyl acetate and methanol extracts of the aerial parts and roots from V. tweediana were also investigated. The extracts showed good to moderated activities.Colegio de Farmacéuticos de la Provincia de Buenos Aire