A Physical Apparatus for the Determination of the Circulation Time of the Blood in Dogs

Abstract

A radical departure from previous apparatus for the determination of blood circulation time is described in detail. The ensemble consists of an ionization chamber (Geiger Counter), a high-voltage (to 2500 volts) power supply, a three-stage amplifying system, and an output circuit for recording the discharges which occur when radiations enter the chamber. A separate electrical circuit is utilized to measure the time interval between the injection of the radioactive material (radium C) in the jugular vein of the dog and its arrival in that part of the femoral artery lying in the adductor canal. The technique of separating radium C from radium emanation is described as is also that of shielding the ionization chamber from extraneous radiations. The record obtained during an experimental test is interpreted as to accuracy and physiological significance and the advantages and disadvantages of the method are outlined

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