Pituitary glands were collected from domestic turkeys and assayed on immature rats and on non-breeding adult sparrows. Various dosages were given. In the rat 25 milligrams of the dry powdered gland produces a minimal reaction. Smaller amounts gave little or no effect while larger amounts gave greater reactions. Daily injections of 5 to 10 milligrams of the powdered gland cause a striking development of the sex glands of sparrows within two weeks
