Published ArticleIn the present study, we report Yb(OTf)3 catalyzed synthesis of biscoumarins by pseudo
three-component reaction of aldehyde and 4-hydroxycoumarin. The synthesized biscoumarins were evaluated
for antimicrobial and insecticidal activity. Results of antimicrobial activity were found to be moderate
to good in terms of zones of inhibition and MIC values against E. coli, P. vulgaris and S. aureus. The compounds
were inactive against the used fungal strains except B4 in case of Penicillium. Insecticidal activity
of the biscoumarins B-1, B-3, B-5 and B-11 was found to be good exhibiting 70-75% mortality effect on
Callosobruchus maculatus