AFM, Maison de la Mécanique, 39/41 rue Louis Blanc, 92400 Courbevoie, France(FR)
Abstract
The objective is to investigate the use of sonication to enhance the release from loaded capsules. Alginate capsules filled with blue dextran and suspended in an aqueous solution were sonicated. The external concentration in blue dextran is found to increase due to sonication, the release step being proportional to the duration and intensity of sonication. Sonication eventually leads to the capsule destruction for longer durations. To conclude on the release mechanism induced by sonication, we have also studied its influence on the capsule properties (geometry, porosity, mechanical properties
