GUIDELINES FOR PREVENTION, CONTROL AND TREATMENT OF INFECTIONS CAUSED BY METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA): Changes and updates of chapter 7.0: Treatment of patients with MRSA infection

Abstract

Meticilin-rezistentni Staphylococcus aureus (MRSA) važan je bolnički patogen u cijelome svijetu, pa i u Republici Hrvatskoj. Stoga se pristupilo izradi smjernica, kojih je svrha smanjiti broj bolesnika inficiranih/koloniziranih sojevima MRSE u zdravstvenim ustanovama i domovima za starije i nemočne osobe u Republici Hrvatskoj te na taj način smanjiti morbiditet i mortalitet koji uzrokuje ova bakterija. Interdisciplinarni tim stručnjaka načinio je Smjernice, koriste}i se internacionalnim publikacijama i smjernicama koje govore o prevenciji i kontroli MRSE, te liječenju i laboratorijskoj dijagnostici MRSE. Snaga preporuka određena je metodologijom CDC/HICPAC, a kategorizirane su na temelju postojećih znanstvenih podataka, teoretske logične podloge, primjenjivosti i ekonomskog utjecaja. Nakon Široke rasprave u stručnim društvima Smjernice su prihvaćene. Nakon toga došo je do određenih izmjena u mogućnostima liječenja infekcija koje uzrokuje MRSA u Republici Hrvatskoj te je poglavlje 7.0. Liječenje bolesnika s infekcijama koje uzrokuje MRSA izmijenjeno i nadopunjeno prema novim mogućnostima liječenja. Preostali dio Smjernica zasada nije izmijenjen.Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen throughout the world, and as well in Croatia. Therefore it was decided to develop guidelines with the aim to reduce the number of patients infected/colonized with MRSA in healthcare facilities and in nursing homes in Croatia, consequently reducing MRSA-related morbidity and mortality. An interdisciplinary team of experts developed these guidelines using existing international guidelines from different countries, and literature reviews about prevention, control, treatment and laboratory diagnosis of MRSA infections. Grades of evidence for specific recommendations were determined using CDC/HICPAC grading system. Categorization is based on existing data, theoretical basis, applicability and economic impact. After a broad discussion in different professional societies, Guidelines were accepted. In the meantime, several new possibilities appeared in the treatment of patients with MRSA infections in Croatia, so the Chapter 7.0 Treatment of patients with MRSA infections is changed and updated according to the new treatment possibilities. The rest of the Guidelines was not changed