The aim of this study is to highlight how tourism development trajectories\u27 (TDTs) boundary-spanning nexuses can be used to prevent abandonment of Egyptian tourism destinations during adversity. This study argues that this aim can be achieved by investigating rational synergistic solutions, which may ultimately help generate a corrected context for destination transformations. However, despite rising concerns about TDTs, many abandoned destinations across the globe are failing to fully integrate TDTs\u27 promises into their transformation strategies and operating models. The findings reveal that capitalizing on TDTs\u27 boundary-spanning nexuses and alignments may help create meaningful change and allow collaborative values to enable a leap forward in the ways of operating destinations. Based on findings, it is concluded that understanding TDTs\u27 interconnected links may build better contexts for destination transformation. A useful destination-operating model to address the interests of destination planners and concerns of struggling businesses for successful transformations is presented