Onaemo, Vivian N

English

UEF Electronic Publications

Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.

Adrenocortical response to ethanol in man.

Alcohol and cardiovascular disease—more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease—a review.

Alcohol and cardiovascular health. The razor-sharp doubleedged sword.

Alcohol and coronary heart disease: the evidence for a protective effect.

Alcohol and coronary heart disease. Circulation

Alcohol and Type 2 Diabetes - Another Paradox Journal of Cardiovascular Risk

Alcohol consumption and carotid atherosclerosis: evidence of dose-dependent atherogenic and antiatherogenic effects.

Alcohol consumption and insulin resistance in young adults.

Alcohol dosing and total mortality in men and women.

Associations between alcohol consumption and insulin sensitivity and cardiovascular disease risk factors: the Insulin Resistance and Atherosclerosis Study.

Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

Beta adrenergic-mediated vasodilator response to insulin in the human forearm.

Binge drinking and mortality after acute myocardial infarction.

Blood flow and muscle metabolism: a focus on insulin action.

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats.

Cardiovascular effects of alcohol.Recent Dev Alcohol 14:135–166,

Cardiovascular Research:

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.

Close relation of endothelial function in the human coronary and peripheral circulations.

Coping with inner feelings and stress: heavy alcohol use in the context of alexithymia.

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation

de Wiel A: The role of alcohol in the anti-low density lipoprotein oxidation activity of red wine. Atherosclerosis 147:365–370,

Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance.

Does regular ethanol consumption promote insulin sensitivity and leanness by stimulating AMP-activated protein kinase? Medical hypotheses;

Drinking frequency, mediating biomarkers, and risk of myocardial infarction in women and men.

Effects of a moderate dose on blood lipids and lipoproteins postprandially and in the fasting state. Alcohol Alcohol

Effects of sympathectomy and nitric oxide synthase inhibition on vascular actions of insulin in humans.

Endothelial dysfunction in insulin resistance and type 2 diabetes.

Endothelial Dysfunction J Am Soc Nephrol 15: 1983–1992,

Endothelial function and nitric oxide: clinical relevance.

Endothelial Function as a Determinant of Vascular Function and Structure: A New Therapeutic Target. Am J Cardiol 1997; 79(SA):3-8 Ginsberg HN. Insulin resistance and cardiovascular disease. The Journal of Clinical Investigation.

Endothelial nitric oxide production and insulin sensitivity. A physiological link with implications for pathogenesis of cardiovascular disease.Circulation

Evidence of cardiovascular protection by moderate alcohol: role of nitric oxide. Free Radic.

Glucose tolerance during moderate alcohol intake: insights on insulin action from glucose/lactate dynamics.

Hemodynamic actions of insulin.

Homogenous Mono-125 I-insulins: preparation and characterization of

Hyperinsulinemia as an independent risk factor for ischemic heart disease.

Hypertriglyceridemia and hyperinsulinemia are potent inducers of endothelin-1 release in humans. Diabetes.

Importance of pattern of alcohol consumption.

Incidence and correlates of hypertension in the Atherosclerosis Risk in Communities (ARIC) study and the Monitoring Trends and Determinants of Cardiovascular Disease (POL-MONICA) project.

Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin.

Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells.

Insulin action and insulin resistance: diseases involving defects in insulin receptors signal transduction and glucose transport effector system.

Insulin action in the vasculature: physiology and pathophysiology.

Insulin and the regulation of cardiovascular system: role of the L-arginine nitric oxide pathway and the sympathetic nervous syatem. In: Luscher TE, editor, The endothelium in cardiovascular disease,

Insulin resistance affects endothelium-dependent acetylcholine-induced coronary artery response. Eur Heart J

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle.

Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death. Diabet Med

Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity.

Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Arterioscler Thromb Vasc Biol

Insulin resistance, hyperinsulinemia, and coronary artery disease: a complex metabolic web.

Insulin transport across capillaries is rate limiting for insulin action in dogs.

Insulin-induced increment of coronary flow reserve is not abolished by dexamethasone in healthy young men.

Insulin, cation metabolism and insulin resistance.

Low ethanol consumption increases insulin sensitivity inWistar rats.

Nitric oxide and peroxynitrite in health and disease.

Pathophysiological implications of insulin resistance on vascular endothelial function.

Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver.

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease.

Quon MJ : Cardiovascular Actions of Insulin. Endocrine Reviews 2007; 28(5):463–491 Muniyappa

Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction Molecular and Pathophysiological Mechanisms. Circulation

Regional myocardial blood flow and glucose utilization during fasting and physiological hyperinsulinemia in humans.

Relationship of glucose tolerance and plasma insulin to the incidence of coronary heart disease: results from two population studies in Finland. Diabetes Care.

Relationship of Insulin Resistance and Related Metabolic Variables to Coronary Artery Disease: A Mathematical Analysis Diabetes Care

Relationship of plasma insulin level to the incidence of myocardial infarction and coronary heart disease.

Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men.

Scandinavian drinking survey: sampling operations and data collection.

Testing for endothelial dysfunction.

The coronary microcirculation in health and disease.

The effects of ethanol on the metabolic activities of the liver. Adv Enzyme Regul 1968;6:467–80.

The FINMONICA Stroke Register: community-based stroke registration and analysis of stroke incidence in Finland,

The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action.

Vascular actions of insulin with implications for endothelial dysfunction. Am J Physio Endocrinol Metab 297: E568-E577,

Insulin resistance, alcohol and coronary heart disease (CHD) mortality

http://epublications.uef.fi/pub/urn_nbn_fi_uef-20120561/urn_nbn_fi_uef-20120561.pdf

Insulin resistance, alcohol and coronary heart disease (CHD) mortality

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