Siitonen, Niina

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UEF Electronic Publications

A Catalog of Published Genome-Wide Association Studies. Available at: www.genome.gov/gwastudies. Accessed February,

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science

A deletion in the alpha2B-adrenergic receptor gene and autonomic nervous function in central obesity. Obes Res

A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nat Neurosci

A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories.

A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science

A genome-wide association study on obesity and obesity-related traits. PLoS One

A genomewide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nat Genet

A genomewide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet

A geographically explicit genetic model of worldwide human-settlement history.

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes

A map of human genome variation from population-scale sequencing. Nature

A new algorithm for haplotypebased association analysis: the Stochastic-EM algorithm. Ann Hum Genet

A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies. Bioinformatics

A novel serum protein similar to C1q, produced exclusively in adipocytes.

A second generation human haplotype map of over 3.1 million SNPs. Nature

A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study.

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology

A tutorial on statistical methods for population association studies. Nat Rev Genet

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet

Abdominal obesity and physical inactivity as risk factors for NIDDM and impaired glucose tolerance in Indian, Creole, and Chinese Mauritians. Diabetes Care

abrogation of adiponectin binding and metabolic actions. Nat Med

Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. Diabetologia

Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes

ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity. Diabetes

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.

Adapting the logical basis of tests for Hardy-Weinberg Equilibrium to the real needs of association studies in human and medical genetics. Genet Epidemiol

Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic women.

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation

Adipocytederived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol

Adipokines in inflammation and metabolic disease. Nat Rev Immunol

Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study.

Adiponectin and adiponectin receptor gene variants in relation to type 2 diabetes and insulin resistance-related phenotypes. Rev Diabet Stud

Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation

Adiponectin and its receptors in non-alcoholic steatohepatitis. Gut

Adiponectin concentrations: a genome-wide association study.

Adiponectin counteracts cytokineand fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1. Diabetologia

Adiponectin expression in human fetal tissues during mid- and late gestation.

Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity.

Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. Diabetes

Adiponectin levels and expression of adiponectin receptors in isolated monocytes from overweight patients with coronary artery disease. Cardiovasc Diabetol

Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. JAMA

Adiponectin multimeric complexes and the metabolic syndrome trait cluster. Diabetes

Adiponectin receptor 1 variants associated with lower insulin resistance in African Americans. Obesity (Silver Spring)

Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations. Diabetologia

Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia

Adiponectin receptors gene expression in lymphocytes of obese and anorexic patients. Diabetes Obes Metab

Adiponectin receptors in human adipose tissue: effects of obesity, weight loss, and fat depots. Obesity (Silver Spring)

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

Adiponectin: a link between obesity and cancer. Expert Opin Investig Drugs

Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year. Clin Chem

AdipoQ is a novel adipose-specific gene dysregulated in obesity.

ADIPOQ polymorphisms, monounsaturated fatty acids, and obesity risk: the GOLDN study. Obesity (Silver Spring)

Adipose tissue in human infancy and childhood: an evolutionary perspective.

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Diabetes

Adrenergic receptor genotype influence on midthigh intermuscular fat response to strength training in middle-aged and older adults.

Allele-specific differential expression of a common adiponectin gene polymorphism related to obesity.

Alpha-adrenergic blockade improves glucose-potentiated insulin secretion in non-insulin-dependent diabetes mellitus. Diabetes

alpha(2)-Adrenoceptor subtypes-mediated physiological, pharmacological actions. Neurochem Int

Alpha2A-adrenergic receptors and type 2 diabetes.

Alpha2B-adrenergic receptor deletion polymorphism and cardiac autonomic nervous system responses to exercise in obese women. Int J Obes (Lond)

An evolutionary framework for common diseases: the ancestralsusceptibility model. Trends Genet

An insertion/deletion polymorphism in the alpha2B adrenoceptor gene is associated with age at onset of type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes

An insertion/deletion polymorphism in the alpha2B-adrenergic receptor gene is a novel genetic risk factor for acute coronary events.

and modernizing influences on the prevalence of type 2 diabetes.

Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism.

Anthropometric and metabolic phenotypes in relation to the ADRA2B deletion/insertion polymorphism in Chinese population.

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat Cell Biol

APPL1: role in adiponectin signaling and beyond.

as a Candidate for Type 2 Diabetes and Insulin Resistance. Diabetes

Assessment methods in human body composition. Curr Opin Clin Nutr Metab Care

Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass index. Nat Genet

Association between dietary factors and plasma adiponectin concentrations in men.

Association between simple anthropometric indices and cardiovascular risk factors.

Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans. Diabetologia

Association of ADIPOR2 with liver function tests in type 2 diabetic subjects. Obesity (Silver Spring)

Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol

Association of insertion/deletion polymorphism of alpha-adrenoceptor gene in essential hypertension with or without type 2 diabetes mellitus in Malaysian subjects.

Association of polymorphisms at the ADIPOR1 regulatory region with type 2 diabetes and body mass index in 77 a Brazilian population with European or African ancestry.

Association of the ADIPOQ rs17360539 and rs266729 polymorphisms with type 2 diabetes: a meta-analysis. Mol Cell Endocrinol

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes

Association. Diagnosis and classification of diabetes mellitus.

Association. Diagnosis and classification of diabetes mellitus. Diabetes Care

Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study. Diabet Med

Autonomic regulation of islet hormone secretion--implications for health and disease. Diabetologia

Banting lecture 1988. Role of insulin resistance in human disease. Diabetes

Brown adipocytes are novel sites of expression and regulation of adiponectin and resistin.

Cardioprotection by adiponectin. Trends Cardiovasc Med

Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA

cDNA cloning and expression of a novel adipose specific collagen-like factor,

Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise. Diabetes Metab Res Rev

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians from Italy: evidence from a family-based study.

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis

Clinical risk factors, DNA variants, and the development of type 2 diabetes.

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.

Candidate gene studies on body size, type 2 diabetes and related metabolic traits genetics of ADRA2B, ADIPOQ, ADIPOR1 and ADIPOR2 in the DPS study population

http://epublications.uef.fi/pub/urn_isbn_978-952-61-0601-4/urn_isbn_978-952-61-0601-4.pdf

Candidate gene studies on body size, type 2 diabetes and related metabolic traits genetics of ADRA2B, ADIPOQ, ADIPOR1 and ADIPOR2 in the DPS study population

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