As flap surgery remains the main technique to close wounds with tendon exposure, the application of artificial dermis in these complex soft tissue wounds is seldom reported. The purpose of this article is to review our experiences in the treatment of tendon-exposed wounds with artificial dermis. This retrospective study included 23 patients with 33 tendon-exposed wounds treated with artificial dermis from 2004 to 2009. Data including patient demographics, wound type, duration from artificial dermis implantation to split thickness skin grafting, surgical complications, and clinical outcome were obtained by chart review. Successful treatment was defined as the formation of golden-yellow neodermis followed by successful split thickness skin grafting. Among the 33 tendon-exposed wounds, 11 were secondary to chronic ulcers, 16 to acute wounds, and 6 to surgical wounds after hypertrophic scar excision. The mean patient age was 49 years. The overall success rate with the artificial dermis technique was 82%, including 63% in the chronic ulcer group, 88% in the acute wounds, and 100% in the surgical wounds. In the success group, 11% of the wounds required repeated artificial dermis implantations. Within the failure group, two wounds were closed by below knee amputation, two by local flap surgery, and two were allowed spontaneous healing as a result of graft failure. We have demonstrated an overall success rate of 82% for tendon-exposed wound closure by using artificial dermis. The outcome was better in surgical and acute wounds than in chronic wounds
