Through independent but unconfirmed physiological mechanisms, ibuprofen (IB) and vitamin E (E) are each proposed to potentially attenuate delayed onset muscular soreness (DOMS) that often accompanies novel eccentric exercise. The purpose of this study was to determine whether or not the use of IB or E reduces the rating of soreness (RS) associated with DOMS or affects the decline in muscular performance that usually accompanies DOMS. A secondary purpose was to determine the accuracy of each group\u27s perception of performance (PP) following the onset of DOMS