This special issue summarizes the major achievements of the US Global Ocean Ecosystem Dynamics (GLOBEC) program and celebrates its accomplishments. The articles grew out of a final symposium held in October 2009 under the auspices of the National Academy of Sciences Ocean Studies Board (http://usglobec.org/Symposium). This special issue updates the US GLOBEC "mid-life" Oceanography issue (Vol. 15, No. 2, 2002, http://tos.org/oceanography/archive/15-2.html), which put forward many of the goals and activities of the program, but was published while field work was still being conducted and results had yet to be synthesized across regional programs. The present special issue highlights the advances in understanding achieved through the synthesis of regional studies and pan-regional comparisons
