Simarouba glaucanbspis a species of flowering tree that is native to Florida in the United States, southern Florida, South America, and the Lesser Antilles. Common names include paradise-tree, dysentery-bark, and bitter wood. Its seeds produce edible oil. Different parts of the tree are used to treat various diseases. The plant has been reported to contain many important phyto constituents which have significant pharmacological importance. The aim of this paper is to highlight the Pharmacological importance of different parts of the plant simaruba glauca and it may give a good platform for future researcher to carry out the various research activities on simarouba glauca plant.nbs