This study aims to determine the level of independence of farmers in the cultivation of seaweed. This research was conducted at the Village East Tomia Patipelong District of Wakatobi. The location was selected purposively (intentionally) by the consideration that the village Patipelong has the potential for seaweed cultivation. Variables observed that the independence of farmers in the cultivation of seaweed (initiative, ability to solve problems on their own, confident and performs himself seaweed farming). Population in this study were farmers who cultivate seaweed which amounts to 152 people. Samples were selected randomly (simple random sampling) with a total sample of 30 respondents, or about 20%. The level of independence of farmers can be determined by using interval analysis. The result showed that the level of independence of farmers in the cultivation of seaweed in the Village Patipelong is high, farmers have to have the initiative, able to solve problems on their own, have a high confidence level and conduct themselves seaweed farming