The Master of Science in Computer Information Systems (CIS) with concentration in Health Informatics (HI) at Metropolitan College (MET), Boston University (BU), is a 40-credit degree program that are delivered in three formats: face-to-face, online, and blended. The MET CIS-HI program is unique because of the population of students it serves, namely those interested in gaining skills in HI technology field, to serve as data analysts and knowledge-based technology drivers in the thriving health care industry. This set of skills is essential for addressing the challenges of Big Data and knowledge-based health care support of the modern health care. The MET CIS-HI program was accredited by the Commission on Accreditation for Health Informatics and Information Management Education (CAHIIM) in 2017