Laboratory Assessment of Molluscicidal Activity of Glinus Oppositifolius (L.) Aug. DC. (Aizoaceae)

Abstract

The negative impact of synthetic molluscicides on the environment and their high cost necessitated search for an alternative approach of using plant extracts for the control of schistosomiasis. The objective of this study was, therefore, to evaluate some crude extracts (butanol and ethyl acetate) and pure products of Glinus oppositifolius aerial part for their molluscicidal effect against schistosome snail intermediate hosts. Assessment of the molluscicidal activity against Bulinus truncatus and Biomphalaria pfeifferi was made by immersion method in accordance with WHO guideline. The results of mortality were statistically analyzed using excel sheets. After 24 hours exposure, BuOH extract has shown the lowest LC50: 64.3 and 91.7 ppm for Bulinus truncatus and Biomphalaria pfeifferi respectively. Moreovernbsp EtOAc extract gave a LC50: 86.2 ppm with Bulinus tuncatus. Although the crude extracts were more active, both crude extracts and pure products from G. oppositifolius revealed a dose-dependent activity on Bulinus truncatus and Biomphalarianbsp pfeifferi. The results showed that G. oppositifolius has molluscicidal activity against B. truncatus and B. pfeifferi snails. Yet, further comprehensive evaluation is recommended for the possible use of G. oppositifolius against B. truncatus and B. pfeifferi