This study focuses on trout fishing in the Great Smoky Mountains and the Blue Ridge Mountains from 1880 to 2017. I begin with a collection of personal narratives of fly-fishing in Tennessee to portray the allure of southern Appalachia trout fishing. I then describe the transition from native Cherokee fishing practices to sport fishing in the Smokies and the Blue Ridge by 1880. I explore a brief history of the National Parks and the United States Forest Service during the early 1900s, and address European fly-fishing influences in the United States during the twentieth century. I examine the habitats of the rainbow trout (oncorhynchus mykiss) and the native brook trout (salvelinus fontinalis) to provide an analysis on inter-species relationship between rainbow and brook trout in mountain streams. I then give an overview of important trout literature in the Smokies and the Blue Ridge through the twentieth and twenty-first centuries