The primary purpose of this study was to determine the relationship of self-reported resistance training to lipid profiles. The study consisted of 10 subjects between the ages of 19 and 35. Participants were assigned to an exercise group or control group based on self-reported resistance training and according to ACSM standards. After means were determined for the data gathered, the exercise group had lower averages of weight, percent body fat, total cholesterol, low-density lipoprotein and triglycerides, as well as, a higher average of high-density lipoproteins. Two sample t-tests were performed to determine significance. It was determined that no significant difference existed between serum lipid profile levels of the control group and the self-reported exercise group. This study is important because it expands our knowledge of the relationship between resistance training (RT) and lipid profiles, relying on self-reported data and focusing on an at-risk population